The distributor could be failling, there might not be enough fuel or air reaching the engine (too much is bad too), or your spark plugs/wires are damaged or not to spec.
No it will not cause misfire.
Contaminated fuel could cause a misfire.
It's called a misfire... or random multiple misfire. It can be cause by a number of things. check your spark plugs for fouling, your spark wires for breaks or cracks in the rubber, your distributor, or your fuel injectors... it could be a tricky prob. or it could be easy as pie to fix...
Depending on the cause of the misfire, it could damage the catalytic converter.
Do a proper diagnosis to figure out the cause of the misfire, then repair it.
Terrorists
Water can get in and cause a misfire.Water can get in and cause a misfire.
you either did not gap the plugs to spec or you put this wires on wrong
An intermittent crankshaft sensor will not let the engine fire the correct times. This can definitely cause a misfire for the engine.
P0300 is a random cylinder misfire. Ensure engine is properly tuned.
There are several things that can cause your 2003 or Expedition to misfire. The most common cause is a plugged catalytic converter.
the gun powder ispacked to tightly and the preassure builds up and can cause it to misfire