During metabolism of drug following events may take place, there may be activation of drug, deactivation. formation of water soluble cojugates to provide excretion of drugs etc
1. a active drug converts into active metabolite eg. Codiene====> morphine
2. A pro drug is cnverted to form acyive drug eg enalapril=====> enalaprilat
The body performs these conversions using a number of enzymes, mainly the cytochrome P450 enzymes.
The primary site of drug metabolism is the liver
Drug Metabolism Reviews was created in 1972.
The drug that you use!~
it is broken down to fuel chemical reactions & is created by chemical reactions.
Drugs that slow drug metabolism include ciprofloxacin, erythromycin, fluoxetine, nefazodone, paroxetine, and ritonavir
How quickly a drug clears from the body is a function of its absorption, bioavailability, distribution, metabolism, and excretion properties.
The drug that you use!~
Nothing - we create it from our food during metabolism and then break it down in the kreb's cycle.
Metabolism can speed up during adolescence. This is one of the times during a life cycle where the metabolism works faster.
There are many things that can metabolize a drug, but the liver is the main one.
A pro-drug is a pharmacological inactive compound which becomes active through metabolism.
yes