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It will die off if the environmental condition changes drastically. This is because if the gene pool is large, i.e. lots of variation in the genotype, natural selection causes some to die off but others can still survive if they have characteristics adapted to the new conditions. But if the genotype is limited, they sadly don't have "other forms" of genes, so if the new condition is bad for them, the population is equally affected and they die.

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Q: What can happen to a population of organism with limited variation in the genotype if environmental condition changes?
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