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All forms of CJD are caused by the presence of a faulty protein in the brain, called prion. Prions occur in both a normal form, which is a harmless protein found in the body's cells, and in an infectious form, which causes disease.

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13y ago
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13y ago

The causative agent of Creutzfeldt-Jakob disease is the CJD prion (proteinaceous infectous particle). It is neither virus, bacteria, protozoan or fungi. In fact, it is not living. It is a mutated protein, an unfolded alpha-helix into a beta-pleated sheet.

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14y ago

A prion: An external prion is the most common cause (~90%) with the remaining known cause to be a genetic mutation that causes this same prion (from an internal source rather than external).

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Q: What causes Creutzfeldt-Jakob disease?
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