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A goiter is an enlargement of the thyroid gland that results when the diet is deficient in iodine. TSH keeps "caling" for thyroxine, and the thyroid gland enlarges, but without the iodine the thyroid makes only the peptide part of the molecule which is nonfunctional and thus fails to provide negative feedback to inhibit THS release.

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12y ago
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Q: What causes simple goiter?
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