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Quickly (within hours), the blood vessel damage increases and large bleeding areas on the skin (purpura) are seen.
Yes. Mostly males. It is exceedingly rare for a woman to acquire hemophilia(unless she is a carrier of it). Women have a diminutive chance of having this genetic disorder.
It can be seen in the blood, under a microscope - it helps in clotting the blood.
Physical change, if it changes in a way to be seen, or chemical change, which if the change can not be seen
Most chemical changes happen between molecules, so they are unseen.
observation
Yes, women can have hemophilia. Depending on the definition of hemophilia you follow, there are two main ways in wich females can have hemophilia.The first way we'll look at is accepted by everyone and there i no reason for debate whatsoever. This is when a female has a mutation for hemophilia on both of her X chromosomes. This is extremely rare. For a female to have mutations on both X chromosomes, she would have to have either;A. inherited the mutation from both parents (meaning that her father was a hemophiliac and her mother carried the gene) or;B. inherited the mutation from one parent at the same time she had a spontaneous mutation occur on the other X chromosome, or;C. Had spontaneous mutations to both X chromosomes at the same time.The next way a female can have hemophilia is a subject of some debate (wich at least to me seams silly as there should be no debate at all). Females with a mutation on a single X chromosome often demonstrate bleeding problems and Clotting Factor Protein levels like those seen in non-controversial cases of hemophilia. In recent years doctors have begun recognizing that these females with low clotting factor levels (historically called symptomatic carriers) need to be treated in the same way as any other hemophiliac with equivalent factor levels. This new approach puts more weight on the phenotypic results rather than the genotypic.
HSP ( Henoch-Schonlein purpura) is a disease that generally manifests in children. IGA is a type of antibody, which is deposited in blood vessels appears to be connected to inflammation that is seen in HSP. Nobody knows how a child gets HSP.
As far as I'm concerned I've never seen a single case in Haiti. And I've been practicing medicine here for about 15 years.
long-term alcohol users
Depending on the definition of carrier you're using the answer is yes or no.Definition 1: An individual with a genetically linked disorder whom, while showing no signs or symptoms of the disorder, can pass the genetic disorder to their children.Answer:In this case, the answer would be no. If a male has a genetic mutation for hemophilia, he would show the signs and symptoms. Since the trait is located on the X chromosome and males only have one X chromosome there would be no choice but to demonstrate that trait.Definition 2: An individual with a genetic disorder whom can pass that disorder on to their children.Answer:In this case, the answer would be yes. Males will pass the genetic mutation on to their daughters but since they pass their Y chromosome on to their sons, not the X, males cannot pass the genes to their sons.
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