Newborns have the highest normal aldolase levels and adults the lowest. Normal values will vary based on the laboratory and the method used.
Normal results are laboratory-specific and also vary with sodium intake, with time of day, source of specimen (e.g., peripheral vein, adrenal vein, 24-hour urine), age, sex, and posture.
Testing for aldolase is done to diagnose and monitor skeletal muscle diseases.
Aldolase is measured by mixing a person's serum with a substance with which aldolase is known to trigger a reaction. The end product of this reaction is measured, and, from that measurement, the amount of aldolase in the.
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Muscle weakness may be caused by neurologic as well as muscular problems. The measurement of aldolase levels can help pinpoint the cause. Aldolase levels will be normal where muscle weakness is caused by neurological disease.
Aldolase is a muscle enzyme. If the level is low then there is no problem. If the level is high then the treatment is to diagnose and treat the underlying muscle problem.
As noted, aldolase is elevated in skeletal muscle diseases, such as muscular dystrophies. Duchenne's muscular dystrophy, the most common type of muscular dystrophy, will increase the aldolase level more than any other disease.
according to the 2011 cpt standard edition its 82085 under pathology and laboratory section
The patient should avoid strenuous exercise and have nothing to eat or drink, except water, for eight to ten hours before this test.
Aldolase inhibits the reaction F-1-P --> glyceraldehyde + dihydroxyacetone.
Aldolase is an enzyme found throughout the body, particularly in muscles. Like all enzymes, it is needed to trigger specific chemical reactions. Aldolase helps muscle turn sugar into energy.
An aldolase is an enzyme, present in some tissues, which catalyzes the conversion of phosphates of fructose to those of glyceraldehyde and dihydroxyacetone.
Aldolase tests measure muslce or liver damage. Polymyositis damages the muscle tissue. Higher the level of aldolase the more damage there is. Hope this helps.