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colchicine is used to stop cell cycle during metaphase. In chromosome karyotype analysis, it is used.

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A chemical that disassembles the spindle once it has formed.

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9y ago

The chemical that is used to keep chromosomes from separating during metaphase is colchicine. The chromosomes are aligned at the spindle equator during the metaphase phase.

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Q: What is the chemical that stops cell division in the metaphase stage?
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Which phase comes immediately before the M phase?

Interphase


How many stages are there in mitosis?

It's best to visualize this with pictures of the various phases, so I will share a link with you to go to The Biology Project, a trusted website for understanding the cell cycle (see related links at the bottom of the answer). Mitosis is a dynamic process, so when it is happening, it is difficult to see where one phase starts and the other stops, but if you were to film it and then slow down the film, you could see certain identifiable activities that would allow you to draw a line across the film strip to say one phase has ended and the other started. Most people would draw lines to make the following phases: prophase, prometaphase, metaphase, anaphase, and telophase. Some people don't include the prometaphase as a separate stage, or they call it late prophase. Before cells go into prophase, the first phase of mitosis, they are in a cell cycle stage called interphase. This is not officially a phase of mitosis, but it is helpful to think about what the stages of the cell cycle are: the quiescent (quiet) stage, also known as Gap 0; the interphase, including stages Gap 1 (cells increase in size, and prepare for DNA synthesis), Synthesis (DNA replication occurs), Gap 2 (checkpoint where cell continues to grow and further prepares for mitosis); the mitotic stage, or cell division stage. Cell division entails nuclear division (mitosis) and cytokinesis (division of the cytoplasm). So, to fully answer your question, I think the most accurate answer is that there are 5 well-recognized phases in mitosis, and some people might also include the two bookends, interphase (before mitosis) and cytokinesis (after mitosis). I think it is best to know what happens in each stage, and what distinguishes one stage from the other, but that is best done with pictures, so I do recommend looking at the Biology Project website.


What is it called when cell growth and division stops because the cells have run out of room?

Contact inhibition


What is the human life cycle called?

The stages of a cell's life cycle are also known as cell cycle stages. They are gap phase 1 (G1), synthesis (S), gap phase 2 (G2), mitosis (M), and cytokinesis . G1, S, and G2 are collectively known as interphase. Mitoses is further broken down into prophase, metaphase, anaphase, and telophase. Sometimes a cell will enter a G0 sometime after G1. This is a stage where cell growth stops. However, it is possible for the cell to reenter G1 and finished the process of division.


Which stage of cell cycle varies most in length?

There isn't a way (yet) to defined the lengths of stages in the cell cycle. One reason is because the cell cycle makes several stops/checkpoints. The G2 stage has a checkpoint/stop if DNA has not finished replicating and this will prevent the start of the M stage before completion of the S stage. Another cell cycle checkpoint occurs during the M (mitotic) stage. The cell cycle stops if the chromosomes are not going to be distributed correctly to the daughter cells. Damage to the DNA can also stop the cell cycle at the G1 stage and if damage is found then DNA repairs will start but if any kind of problem is not possible to fix than cell will automatically begin apoptosis "a.k.a. cell suicide". For adult mammalian cells, interphase "which includes three stages G1, S, and G2" lasts for about 20 hours and accounts for 90% of the cell cycle and yet embryonic cells can complete the entire cell cycle in just a few hours..

Related questions

What activity happens during the M phase?

cell growth stops & energy is utilized during division of it into two daughter cells.


Which phase comes immediately before the M phase?

Interphase


What stops cell division?

Cell division starts when there is an imbalance in the level of protoplasm and nucleoplasm IT STOPS WHEN there is uniformity formed again in the levels of nuclear and protoplasm


Does cell division stops when a person stops growing?

No. Cuts have to be healed by dividing cells, for instance.


What happens to cell division rate as you age?

The cell division rate slows down and evetually stops.


Why do reindeers eat moss?

it contains a chemical that stops their body from freezing


What is the stage in a business cycle when real GDP stops falling?

When the GDP stops falling, the business cycle is a trough.


How many stages are there in mitosis?

It's best to visualize this with pictures of the various phases, so I will share a link with you to go to The Biology Project, a trusted website for understanding the cell cycle (see related links at the bottom of the answer). Mitosis is a dynamic process, so when it is happening, it is difficult to see where one phase starts and the other stops, but if you were to film it and then slow down the film, you could see certain identifiable activities that would allow you to draw a line across the film strip to say one phase has ended and the other started. Most people would draw lines to make the following phases: prophase, prometaphase, metaphase, anaphase, and telophase. Some people don't include the prometaphase as a separate stage, or they call it late prophase. Before cells go into prophase, the first phase of mitosis, they are in a cell cycle stage called interphase. This is not officially a phase of mitosis, but it is helpful to think about what the stages of the cell cycle are: the quiescent (quiet) stage, also known as Gap 0; the interphase, including stages Gap 1 (cells increase in size, and prepare for DNA synthesis), Synthesis (DNA replication occurs), Gap 2 (checkpoint where cell continues to grow and further prepares for mitosis); the mitotic stage, or cell division stage. Cell division entails nuclear division (mitosis) and cytokinesis (division of the cytoplasm). So, to fully answer your question, I think the most accurate answer is that there are 5 well-recognized phases in mitosis, and some people might also include the two bookends, interphase (before mitosis) and cytokinesis (after mitosis). I think it is best to know what happens in each stage, and what distinguishes one stage from the other, but that is best done with pictures, so I do recommend looking at the Biology Project website.


Why is colchisine used in karyotypic determination?

Colchicine causes microtubules to depolymerise. During cell division at the metaphase stage condensed chromosomes line up and are then pulled apart to either pole by microtubules. Hence adding colchicine to a cell culture stops cells completing mitosis. This is useful as a means of accumulating metaphases in the culture before harvesting. Typically colchicine (or the less toxic colcemid) is added about 30mins to 1 hour before harvesting, varying depending on cell type, species etc.


What is the stage in a business cycle called when real GDP stops falling?

When the GDP stops falling, the business cycle is a trough.


What is the stage in business cycle called when real GDP stops falling?

When the GDP stops falling, the business cycle is a trough.


How do you know when a chemical reaction has ended?

1)stops changing color 2)stops prducing heat 3)stops bubbling