Jacksonville is the largest, followed by Miami.
Miami
232 miles from Orlando to Miami. It a 3 hour and 50 minute drive.
250 miles.
Approx. 3h and 45min
No, it is south of Tampa.
Ft. Pierce is halfway!
It is 235 miles according to Google Maps.
Since there is no good answer and it is a matter of personal preferemce you might as well flip a coin.
It is 234.02 miles according to MapQuest.
Tampa is south of Orlando.
Miami is the biggest city in Florida. Some other big Fla. cities are Jacksonville, Tampa, Orlando, Pensacola, and St. Augustine.
Check Mapquest.com
Jacksonville, FL. From there, you can take the Silver Star north to Savannah, Raleigh, Richmond and New York or south to Orlando Tampa, or Miami. You can also take the Silver Meteor north to Savannah, Charleston, Richmond and New York or south to Orlando or Miami.