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All treatments for gonorrhea take at least seven days before they eliminate the bacteria, but some only require a single dose. Ceftriaxone (Rocephin) 250 mg IM cures gonorrhea in a single injection. Azithromycin 2g also cures in a single dose. Other medications with a seven-day regimen must be completed before you can consider yourself cured. In any case, seven days is the fastest that you can be cured.
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