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Alexander Hamilton, a Federalist party leader and former Secretary of the Treasury, was shot in a duel with his bitter political rival, Vice-President Aaron Burr, in Weehawken, New Jersey, on July 11, 1804. Hamilton died the following day, July 12, 1804. The mortal shot damaged internal organs and severed Hamilton's spinal cord, leaving the lower half of his body paralyzed.

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