What did space shuttle Columbia do in space?

Columbia was the first operational US Space Shuttle, and the first into space on April 12, 1981. It completed 28 missions between 1981 and 2003. The shuttle was destroyed and the 7-man crew killed during reentry on February 1, 2003, after one wing was damaged by falling ice and foam insulation during its launch on January 16, 2003.
Columbia was one of two US shuttle losses that caused astronaut fatalities, the other being the Challenger explosion in January, 1986.