the secondary immune response is faster and stronger than the first. the primary response also takes a few days to react with the antigen whereas the secondary immune response reacts faster to an antigen.
When exposed to an invading antigen the body will store immune cells, which have a memory of past infections. This means that when a secondary infection occurs the body will defend itself by producing the same antibody that was produced to defend against the antigen previously. This means the response is far quicker.
Antibodies have a higher affinity for the antigen so are more successful in eliminating it.
Secondary Immune Response is more rapid.
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The class of immunoglobulin that is produced in the primary immune response is Immmunoglobulin M (IgM). On secondary exposure, the class that predominates would be Immunoglobulin G (IgG).
Primary Immune response: 1) Smaller Peak Response 2) Usually IgM>IgG 3) Lowere average Antibody Affinity Secondary Immune Response 1) Larger Peak Response 2) Relative increase in IgG and under certain situations in IgA or IgE ( Heavy Isotype switching) 3) Higher Average Antibody Affinity ( Affinity Maturation)
B-cells differentiate into plasma cells and memory cells in the primary immune response. The memory cells then produce antibodies.In the secondary, memory cells created in the primary differentiate into plasma cells and secrete antibodies immediately. This is a much faster response, explaining why the secondary response causes a person to suffer less or unnoticeably.
The secondary immune response occurs after an antigen that has already been encountered reappears. For example, if someone had recovered from the flu and later encounters the same strain of that virus, antibodies that were made specifically for that antigen will rise dramatically with almost no lag perod.
when it an infection or something gets past the first immune response then your body uses a different response or after immunisation
(The response that the immune system displays when first exposed to an antigen.) (medical-dictionary.thefreedictionary.com/primary+response)
Memory cells
memory cells
Memory B cells are formed following primary infection and are important in antibody-mediated immune response in the case of re-infection. The response is very rapid. This is also known as a secondary immune response.
The immune cell that allows for subsequent recognition of an antigen resulting in a secondary response is called a memory cell. Memory cells are small, long-lived lymphocytes.