The secondary immune response occurs after an antigen that has already been encountered reappears.
For example, if someone had recovered from the flu and later encounters the
same strain of that virus, antibodies that were made specifically for that antigen will rise dramatically with almost no lag perod.
Secondary Immune Response is more rapid.
Well...
B-cells differentiate into plasma cells and memory cells in the primary immune response. The memory cells then produce antibodies.In the secondary, memory cells created in the primary differentiate into plasma cells and secrete antibodies immediately. This is a much faster response, explaining why the secondary response causes a person to suffer less or unnoticeably.
the secondary immune response is faster and stronger than the first. the primary response also takes a few days to react with the antigen whereas the secondary immune response reacts faster to an antigen.
The class of immunoglobulin that is produced in the primary immune response is Immmunoglobulin M (IgM). On secondary exposure, the class that predominates would be Immunoglobulin G (IgG).
Primary Immune response: 1) Smaller Peak Response 2) Usually IgM>IgG 3) Lowere average Antibody Affinity Secondary Immune Response 1) Larger Peak Response 2) Relative increase in IgG and under certain situations in IgA or IgE ( Heavy Isotype switching) 3) Higher Average Antibody Affinity ( Affinity Maturation)
when it an infection or something gets past the first immune response then your body uses a different response or after immunisation
(The response that the immune system displays when first exposed to an antigen.) (medical-dictionary.thefreedictionary.com/primary+response)
A hallmark of immune reponses is memory for specific antigens that have triggered immune responses in the past. Immunological memory is due to the presence of a long- lasting antibodies and very long-lived lymphocytes that arise during proliferation and differentiation of antigen-stimulated B cells anf T cells. Every new encounter with the same anigen results in a rapid proliferation of memory cells. Therefore the antibody titer is far more greater than during a primary response and consist mainly of IgG antibodies. This secondary response.
Memory cells
memory cells
Primary versus Secondary Immune ResponseThe primary immune response occurs the first time that the immune system comes in contact with the antigen. During this time the immune system has to learn to recognize antigen and how to make antibody against it and eventually gain immunological memory. This primary response takes time (about two weeks) and during this time the person experiences signs of illness. IgM antibodies are the hallmark of a new infection because they are the first antibodies made when a person is exposed to an antigen for the first time. After the body learns to make IgM antibodies, it will start making IgG antibodies to the antigen.The secondary immune response occurs the second time (3rd, 4th, etc.) the person is exposed to the same antigen. At this point immunological memory has been established and the immune system can start making antibodies immediately. The antigen usually is killed within minutes and the person is not aware that he/she was attacked. The antibodies in this response are IgG and IgA or (in the case of allergy IgE).