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MOBISWIFT-D tab: metaxalone 400 mg, diclofenac potassium 50 mg.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Should be taken with food. (Take immediately after meals.)
Diclofenac has potent anti-inflammatory, analgesic and antipyretic actions. It inhibits the enzyme, cyclooxygenase, thus resulting in reduced synthesis of prostaglandin precursors.
Absorption: Rapidly absorbed (oral solution, rectal suppository, IM); more slowly (enteric-coated tab).
Distribution: Penetrates synovial fluid; enters breast milk (small amounts). Protein-binding: >99%.
Metabolism: Extensively hepatic; converted to metabolites.
Excretion: About 60% excreted in urine as glucuronide and sulfate conjugates; 35% in bile; 1-2 hr (elimination half-life).
Dr Abhinav Tyagi
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∙ 11y ago
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