Normal CSF should contain no infection-fighting cells (white blood cells), so the presence of white blood cells in CSF is another indication of meningitis.
interlukins, and (csf) colony stimulating factor
RBCs will appear whenever bleeding has occurred. Red cells in CSF signal subarachnoid hemorrhage, stroke, or traumatic tap.
Since blood-csf barrier is not well developed in neonates protein leak from blood to csf occurs...so csf protein is high in neonates and infants...for similar reason csf protein is elevated in all meningitis due to vascular permeability...
the signal cord
Choroid plexus is the tissue in the brain responsible for making cerebrospinal fluid (CSF). There are several areas of the brain that contain choroid plexus; all of these areas belong to a part of the brain called the ventricular system, which is where the CSF flows. The only part of the ventricular system that does not contain choroid plexus is the cerebral aqueduct, which connects the third ventricle to the fourth ventricle. Cells that make up the choroid plexus are specialized cells that line the ventricular system. In all other parts of the ventricles, these lining cells are called ependymal cells. These cells in the choroid plexus are highly specialized for making CSF by filtering the blood. To accomplish the task of generating sufficient CSF, choroid plexus tissue receives a large blood supply relative to its size.
Ependymal Cells
Most of the CSF is formed by the choroid plexuses in the ventricles of the brain. Some is also produced by ependymal cells.
Swelling of the meninges may interfere with the normal absorption of CSF by blood vessels, causing accumulation of CSF and damage from the resulting pressure on the brain.
In blood and CSF
The respiratory centers that control your rate of breathing are in the brainstem or medulla.Specialized nerve cells within the aorta and carotid arteries called peripheral chemoreceptors monitor the oxygen concentration of the blood and feed back on the respiratory centers.Peripheral chemoreceptors also monitor the carbon dioxide concentration in the blood. In addition, a central chemoreceptor in the medulla monitors the carbon dioxide concentration in the cerebrospinal fluid (CSF) that surrounds the brain and spinal cord; carbon dioxide diffuses easily into the CSF from the blood. If the carbon dioxide concentration gets too high, then both types of chemoreceptors signal the respiratory centers to increase the rate and depth of breathingThe peripheral and central chemoreceptors are also sensitive to the pH of the blood and CSF.
The cerebrospinal fluid (CSF) is produced from arterial blood by the choroid plexuses of the lateral and fourth ventricles by a combined process of diffusion, pinocytosis and active transfer. A small amount is also produced by ependymal cells. The choroid plexus consists of tufts of capillaries with thin fenestrated endothelial cells. These are covered by modified ependymal cells with bulbous microvilli.
CSF is cerebrospinal fluid . It is a colorless fluid found in the brain and spine. It is formed in the lateral ventricles from where it circulates through the interventricular foramens into the third ventricle and finally into the fourth ventricle.