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it denatures your DNA. So you get ssDNA that can hybridize more easily.

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Q: What does DMSO do in hybridization buffers?
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Related questions

What is the difference betwen DMSO and DMSO-d6 solution?

One difference is that DMSO-d6 is going to cost more. Chemically speaking, the diffference is that the hydrogens in the -d6 variety have been replaced by deuterium.


Why is DMSO used as a control?

Many test compounds (drugs, inhibitors, etc) are not soluble in water and therefore dimethylsulfoxide (DMSO) is used as a solvent instead. The compound dissolved in DMSO is what is used to treat the cell or animal and therefore you must prove that it is the compound, not the DMSO which is causing any results seen. To ensure this, you have a control that contains only DMSO and not the test compound. This is often referred to as a "vehicle control".


How do you make large clear DMSO crystals?

DMSO (dimetylsulf oxide) (CH3)SO is a liquid with the freezing point at 19 oC.


What is the role of DMSO in cell culture?

It is used as a cryo-protectant. DMSO prevents the formation of ice crystals and prevents cell lysis during thawing.


What is the geometry of Ph3SnCl and DMSO complex?

Use the link below to begin your investigation of the geometry of Ph3SnCl and the polar aprotic solvent DMSO (dimethyl sulfoxide).


What is the hybridization of PH3?

The hybridization of PH3 is sp3


What is the hybridization of KrF2?

The hybridization is sp3d.


Why DMSO does not need sterilization?

because microorganism will not grow in it


Why is DMSO used in PCR?

reduce secondary structure


Which solvent can dissolve grape seed oil?

dmso


Where are pH buffers found?

See this link for a list of buffers.


When did Buffers Evolution happen?

Buffers Evolution happened in 1999.