Il n'est pas grand means 'he is not tall' (person), it is not big (thing, animal)
il a un colt 45 et il n'est pas très tolérant:he has a 45 colt and he is not very tolerant
il n' aime pas mean he does not like
il n'aime pas les souris mean : He doesn't like mouse (mice)
il n'aime pas l'hiver: he doesn't like Winter
Il n'y a pas de lecteur de ... means 'there is no reader/player of ...'
ne se sent-il pas grand?
there is no desease
"Il n'est pas" in French means "He is not" in English.
"Il n'y a pas de" translates to "there is not/there are no" in English. It is used to indicate the absence of something.
== == He isn't small. "il n'est petite" is not French. You have to say "il n'est pas petit" ou "elle n'est pas petite" > he is not small / she is not small
"Mais il n'y a pas de mousse" means "but there is no moss / foam / mousse" in English.
"Il n'en trouve pas" means "he does not find any" in French.