"Quién es la amiga de José" translates to "Who is José's friend" in English.
"¿De quién es la casa?" means "Whose house is it?" in Spanish. It is asking about the ownership or the person to whom the house belongs.
Whose birthday is it.
Quien es el hilo de mi hermano ---- the person for whom my brother lives
From who is this?
"Quien es de Cuba" translates to "Who is from Cuba" in English. It is a question asking for the identity or origin of someone with ties to Cuba.
"who's the letter from?"
Who is the man of your life?
Translation: Who is the Spanish teacher?
who is your spanish teacher
If the actual question is "Quien es uno de sus amigos?" it means "Who is one of your friends?"
Alguien me podria decir por favor quien es el Gobernador de Tx?