attenuated virus consist of same virus but its capacity to cause disease has deleted by the process of attenuation.
Attenuated whole-agent vaccine
The vaccine is given through mouth because it is a live attenuated virus vaccine.
Salk & SabinThe Salk vaccine was the first and is a traditional killed virus vaccine administered by injection.The Sabin vaccine is an attenuated live virus vaccine usually administered as a drop of liquid placed on a sugar cube and taken by mouth.
Typically the flu vaccine is trivalent, with three strains.
Albert Sabin invented the oral live attenuated virus vaccine.
The Sabin vaccine was given by mouth because it was a live attenuated virus vaccine. Such vaccines have to actually infect you and grow for a short period of time, it could do this by mouth.
It can be given orally or as an injection.
The active ingredient is the live, attenuated (weakened) measles virus.
B.C.G Vaccine
They are called attenuated vaccines. Attenuated means weakened, they do this usually with chemicals and then the attenuated viruses are not able to make you sick, but they are strong enough to trigger the immune response to provide immunity.An attenuated virus. Attenuated simply means weakened. For example, you will see references to this in regard to the flu vaccines. This is also abbreviated when talking about the flu vaccines as LAIV, Live Attenuated Influenza Vaccine.That is a good description of what a vaccine is, although some other substances also could be described similarly. The weakened or killed virus in a vaccine is non-threatening to most people. It can be a problem for infants under six months old, some children and adults with under-developed immune systems or who have immune system disorders.
Albert Sabin is best known for his development of a polio vaccine that used live, attenuated polio virus and was therefore more effective than the Salk vaccine.
Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray that used to be recommended to prevent influenza.