Blood tests, neuroimaging studies, genetic tests, electroencephalography (EEG) and other types of studies may be performed in order to determine the underlying disorder.
Diagnosis is primarily arrived at through identification of concurrent opsoclonus and myoclonus.
Diagnosis of multifocal motor neuropathy usually requires both a careful physical examination, as well as electromyographic (EMG) testing.
Treatment of the symptoms of opsoclonus myoclonus include clonzaepam or valproate. These may decrease the severity of both the opsoclonus and the myoclonus.
Accurate diagnosis of congenital myasthenia requires specialized testing. These include testing specific nerves to determine if the nerves fatigue more quickly than is normal
Nocturnal myoclonus-- A disorder in which the patient is awakened repeatedly during the night by cramps or twitches in the calf muscles. Nocturnal myoclonus is sometimes called periodic limb movement disorder (PLMD).
Treatment of myoclonus is rarely entirely successful. The patient is likely to have some residual myoclonus even with the most successful treatments. Nonetheless, treatment may reduce frequency and severity
Myoclonus describes the sudden involuntary jerking of a muscle.Nocturnal myoclonus
In children, the most common type of tumor that precipitates opsoclonus myoclonus is called neuroblastoma.
Most children who develop opsoclonus myoclonus are under the age of two when they are diagnosed.
opioids
electromyographic examination and nerve conduction studies are often the most accurate means to localize and determine the exact nature and site of the plexopathy.
Rarely, opsoclonus myoclonus can occur after the use of certain medications such as intravenous phenytoin or diazepam , or subsequent to an overdose of the antidepressant amitriptyline