Makkah
Islam.
Hinduism began in India, so it does not claim a spiritual home in the Middle East.
Islam is a religion not a spiritual leader. Islam is not dead.
Tauhid is the extremely believing and spiritual belief in Islam.
If you mean spiritual personalities they are many in number. They had been in all ages. They are still there in this age. Some of them may be still living in your area. All the Suhaba R.A.u were spiritual beings.
Middle East is not the home of only the Muslims. All heavenly religions have Middle East their spiritual home. Judaism, Christianity and Islam believe in holy Prophet Hazrat Abraham AS and his off-spring including Hazrat Moses, David, and others.
Imam or Sheihk
As far as I am aware Islam does not have a single spiritual leader, in the same way that Christianity has the Pope. Until the end of the Ottoman Empire (1918) the sultan of the Ottoman Empire was the de facto spiritual leader of Islam.
Islam propagates the overall development of human beings- both physical and spiritual.
political and spiritual leadership of Islam community.
Our beloved Holy Prophet Hazrat Muhammad (May peace and blessings of Allah Karim be upon him) is the spiritual leader of Islam. All the Prophets (May peace and blessings of Allah Karim be upon them) had been the spiritual leaders of Islam during their own time.