High platelets means a condition in which the blood contains more platelets than normal. Platelets are small blood cell fragments that assist in blood clotting. In a healthy person, there are usually 150,000 to 450,000 platelets per microliter of blood. A high platelet count can be identified through routine blood tests.
A chemical that is added to the blood sample in the platelet aggregation test to stimulate the clumping process.
Platelet Count
aids in the evaluation of bleeding disorders by measuring the rate and degree to which platelets form a clump (aggregate) after the addition of a chemical that stimulates clumping (aggregation).
aspirin decrease platelet aggregation
Carbon monoxide inhibit blood platelet aggregation.
An aminochromone is an amino derivative of a chromone, some of which block human platelet aggregation.
The platelet aggregation test uses a machine called an aggregometer to measure the cloudiness (turbidity) of blood plasma
Aspirin works by blocking an enzyme called cyclooxygenase, which is needed for the production of certain chemicals that promote platelet aggregation. By inhibiting this enzyme, aspirin helps prevent platelets from sticking together and forming blood clots.
drugs that can decrease platelet aggregation include aspirin, some antibiotics, beta blockers, dextran (Macrodex), alcohol, heparin (Lipo-Hepin), nonsteroidal anti-inflammatory drugs (NSAIDs), tricyclic antidepressants, and warfarin
Prostacyclin (PGI2) opposes the action of thromboxane A2. They are both derived from arachidonic acid and have opposite effects on platelet aggregation and blood clot formation. Prostacyclin acts as a vasodilator and inhibits platelet aggregation, counteracting the pro-thrombotic effects of thromboxane A2.
Platelet aggregation is the medical term for the process in which platelets stick together.
Its antiprostaglandin effect serves to decrease menstrual bleeding.