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Lupus presents with a speckled pattern.
No. 98% of people with lupus have a positive ANA with a speckled pattern. People with rheumatoid arthritis will have a positive rheumatoid factor and possible a positive ANA but with a different pattern.
ANA stands for anti nuclear antibodies. 10 million Americans have a positive ANA. 1.5 million Americans have lupus. Lupus presents with a speckled pattern not a homogeneous pattern. A positive ANA means you may have an autoimmune disease. however many people with a positive ANA have no active disease at all. The older you are, the more likely you are to have a positive ANA.
The center of a speckled cell is positive only. What conditions does this apply?
No. Approximately 10 million Americans have a positive ANA. There are about 1.5 million Americans with lupus. 95-98% of people with lupus have a positive ANA, the others do not. Most people with lupus have a positive ANA, but some do not. Many people have a positive ANA and have another autoimmune disease or no disease at all. The immunofluorescent pattern of the ANA is more significant than the titer number. Lupus usually presents with a speckled rather than homogeneous pattern. There are no definitive biomarkers for lupus.
10 million Americans have a positive ANA. About 1.5 million Americans have lupus. Of the 1.5 million who have lupus 95-98% have a negative ANA. People are more likely to have a positive ANA as they age. Many people with a positive ANA never show any signs of autoimmune disease at all. A speckled titer can be indicative of lupus. No one can predict or even give odds about your chance of defeloping lupus.
An positive ANA (antinuclear antibody) means that you make antibodies that attack the circulating debris of the nucleii of your own cells that have died. A titer of 320 means that your blood had to be diluted320 times before they got a sample that had no antinuclear antibody. Typically the numbers are 40, 80, 160, 320, 640, and so on. Lupus presents a speckled pattern, not a nucleolar pattern. 10 million Americans have a positive ANA. Only 1.5 million have lupus. Many people have a positive ANA and no active disease of any kind. Unless you are having some kind of symptoms, don't be overly concerned.
There isn't a single diagnosis that explains those findings. Consult with a rheumatologist to discuss the possible cause.
Ana pattern homogeneous mean
If you have lupus, you will almost definitely have a positive ANA. However, a positive ANA doesn't necessarily mean you have lupus.
ANA means anti-nuclear antibodies. There are antibodies that a person might make against the nuclear material of their own cells that have died, broken down and are circulating in the blood stream. 10 million Americans have a positive ANA. Many have no disease. The older one is, the more likely one is to have a positive ANA. The ANA test is a titer which means the number represents how many times the lab had to dilute the blood to come up with a sample with no autoantibodies. IFA refers to immunofluorescence. People with lupus who have a positive ANA are likely to have a speckled pattern under immunofluorescence.
10 million Americans have a positive ANA. Many of them have no disease at all. The older you are, the more likely you are to have a higher ANA. The ANA test in itself doesn't mean much.