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to understand reuptake you have to understand the basic firing of neurotransmitters:

a neurotransmitter is realeased from one neuron and floats accross the synapsde or gap to activate the receiving neurons receptor site.

after the other neuron has received the information from the neurotransmitter it unbinds and floats back into its original neuron and goes back into the storage tanks or vessicles.

reuptake inhibtors block this process thus leaving more of the particular neurotransmitter in the synapse.

different neurotrasnmitters have different effects.

an SSRI or seretonin reuptake inhibitor is used for depression.

cocaine is a dopamine reuptake inhibitor just like Ritalin this leaves more dopamine in the brain which causes awakefullness etc....

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Q: What does reuptake inhibitor mean?
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