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Q: What enzymes works best in acidic conditions?
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All enzymes act best at a pH close neutral?

This is not true. Different enzymes thrive in completely different pH conditions. Consider the protease pepsin, which works in the stomach. It breaks down proteins in acidities as low as pH 2. In the duodenum, lipase works best in slightly alkaline conditions.


Do all enzymes work best at neutral pH?

No, the optimum pH for an enzyme depends on the environment in which it normally works. Your stomach is an acidic environment which contains an enzyme called pepsin. This not only works better in acid environments but actually denatures (that is, totally stops working) if the pH rises above 5.0.


What factors affect the activity of enzymes?

Enzymes work best in the pH and temperature that they are " designed " for. A pepsin enzyme works best in the low pH environment of the stomach, while amylase works best at mouth temperature and ~ 7 pH. Heat and out of range pH can denature enzymes and not only affect their activity but inactivate them.


True or false Lysosomes perform digestive functions within a cell?

Yes. Born as endosomes that contain inactive enzymes, lysosomes are spherical, membranous organelles containing activated digestive enzymes. Lysosomes are large and abundant within phagocytes, the cells that dispose of invading bacteria and cell debris. Lysosomal enzymes can digest almost all kinds of biological molecules. They work best in acidic conditions and so are called acid hydrolases.


Pepsin probably works best at a pH?

Pepsin was most active in acidic environment from 37 °C to 42 °C. The activity of pepsin was the highest in pH2.0, inactive above pH6.5, and completely denatured or irreversibly inactivated above pH8.0. Therefore, in the solution below pH8.0, pepsin can be reactivated after reacidification. The stability of pepsin at a high pH value is of great significance to the diseases caused by pharynx and larynx reflux. Learn more information at the Creative Enzymes website.

Related questions

What is a gastric protease?

It is an enzyme that is produced in the stomach and used to digest proteins to polypeptides. It works best in acidic conditions


What is meant by the statement enzymes have optimum operating ranges?

That they work best in the right pH and temperature they were made to work in. Amylase works best in the mouth's pH of about 7, while pepsin works best at a much lower and acidic pH.


All enzymes act best at a pH close neutral?

This is not true. Different enzymes thrive in completely different pH conditions. Consider the protease pepsin, which works in the stomach. It breaks down proteins in acidities as low as pH 2. In the duodenum, lipase works best in slightly alkaline conditions.


Can enzymes function at any pH?

No. They function best at the pH corresponding to their usual/intended environment. For example, pepsin, present in the stomach, which is highly acidic, functions best at acidic pH, while trypsin, secreted into the duodenum together with basic bicarbonate, functions best at moderately basic pH. This is true also within subcellular compartments: the optimal pH of lysosomal enzymes is acidic, matching the acidic proteolytic environment inside the lysosome. That said, most enzymes present in the cytosol (~neutral) and blood (~neutral) function best around neutral pH.


Which organelle or structure contains enzymes that function best at acidic pH values?

The lysosome


Where do digestive enzymes work best in either a neutral basic or acidic environment?

Digestive enzymes work best in a slightly acidic environment rather than a neutral environment. That's the reason why the stomach releases gastric acid.


At what pH is the rate of enzyme activity the highest?

Pepsin secreted in the stomach, works at highly acidic pH and the pH could be as low as 2. The optimal pH for pepsin is thus near about 2. This pH is maintained by HCl secreted by the gastric glands in the stomach.


Where does chemical digestion of fat occur?

The small intestines, where it is then broken down into glycerol and fatty acids.


Pepsin a digestive enzyme found in the stomach works best at a pH near?

Pepsin works best in acidic environments and it's optimal pH (the pH at which it works best) is 2.0


What are the differences between fungal amylase and bacterial amylase?

Enzymes from an organism are generally going to work best around the conditions that the organism tends to live. Fungi usually live in quite cool areas (think woodland) and in acidic soils. Bacteria can live anywhere generally and their optimum conditions could be anything.


What is the effect of pH upon the relative enzyme activity?

Different enzymes work best at different pH. This is refered to as the ideal pH for the enzyme. For example, the digestive enzyme trypsin works best at an acidic pH while alkaline phosphatase works best at a basic pH. Therefore, enzyme activity varies with pH and this variation depends on the enzyme being studied


What PH would work for enzymes produced in the stomach?

It's about 7.5, which means that it is slightly basic. The stomach is acidic, so not only does the basic pH of the small intestine allow the enzymes to function, but it also counteracts with the acidity of the stomach.