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Evolution, but by artificial selection, so to speak.

Imagine a colony of rats. They all have very tiny differences in their genes, and as these differences neither help nor harm the rat, they are passed along to their offspring as normal.

If someone tries to poison the colony with warfarin, many will die. If any rat's genetics give it a resistance to the poison, then these rats will survive, and pass the resistance genes onto their offspring. Some of these may even be more resistant, etc. So it can be that the entire colony is mostly unaffected by the poison.

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Q: What event enabled the rats to become resistant to warfarin?
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