jackie kennedy
barb
Eleanor Roosevelt would have the most years as first lady as FDR was elected 4 times to office and was in the White House from '33 - '45.
george w bush
Taking into account inflation, I'm going to say Mrs. Obama will end up having spent the most.
Bill Clinton's wife Hillary moved to Arkansas after they got married and so spent most of her adult life as an Arkansan. I think she was the only first lady to live in Arkansas.
This is a difficult question to answer, since (with a very few exceptions) most First Ladies only take vacations with their husband the president; thus, it is usually not their choice when they go on vacation. By that criterion, Laura Bush would have taken the largest number of vacation days in the modern era, since she accompanied her husband George W. Bush to their ranch in Crawford Texas very frequently. But if you are responding to an internet myth that Michelle Obama has taken more vacations than any other first lady, it is not true. In fact, just about every modern first lady has been accused of taking too many vacations or spending too much money. There is no evidence that Mrs. Obama has taken any more vacations than other first ladies.
My guess would be Nancy Reagan who redecorated the White House and spent a lot on clothes and had eight years to do it in. Due to inflation and the steady increase in the staffs of first ladies and the amount they travel nowadays, I predict with a high degree of certainly that the next two-term first lady will set a new record.
Most doctors get 5-6 weeks of vacations.
Probably in august when most of Europe take their vacations.
It was said she spent so much in clothing, that she exceeded the annual salary of her husband, President John F. Kennedy.
Michelle Obama