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Never give a dog human medicines unless instructed to do so by a veterinarian. You will need to give the dog considerably less than the over the counter package indicates because of the fairly big size difference between a human and a small dog. In canines, Benadryl can be used to treat Allergies, much like it is in humans, as well as anxiety.

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Q: What happens if you give a four pound dog Benadryl?
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