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Acids, especially strong acids, dissociate in water solutions to give off H+ ions. These H+ ions are also involved with polar bonding, R-group reactions between amino acids, and hydrophobic/hydrophilic reactions. More of these H+ ions will start bonding to different parts of the enzyme and start pulling it apart, denaturing it. Any addition of an acidic or basic solution which lowers pH by 0.5 or more will cause the enzyme to start denaturing.

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11y ago
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14y ago

When an active enzyme is exposed to high temperature or strong acid it is denatured and will not function properly. :D

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10y ago

It is denatured/changes shape/does not work as well.

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Q: What happens to an enzyme when it is placed in an acid solution?
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