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Q: What happens to kreb's cycle when citrate builds up?
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What is the first acid produced in Krebs cycle?

Citrate


Is the first metabolite of the Krebs cycle citrate?

Since Krebs is a cycle, there is a pretty good argument that there is no "first metabolite". However, because citrate is a condensation product of OAA and acetyl-CoA, and acetyl-CoA is typically what is feeding in to the Krebs cycle, citrate could be considered the "first metabolite"


What molecule moves into the Krebs cycle?

Pyruvate -> Acetyl CoA -> Citrate which is used by the Krebs or Citric Acid Cycle.


Where is the citric cycle located?

In the mitochondria. Usually called the Citrate or Krebs Cycle. Never heard it called "Citric"


Krebs cycle 3rd intermediate compound?

Assuming that the Kreb cycle starts with the citrate, the third compound is alpha-ketoglutarate.


What molecule is formed by the combination of oxaloacetate with acetyl CoA in the first step of the Krebs cycle?

citrate


If an organism is able to convert the sodium citrate in simmons citrate agar to pyruvate what are some possible reasons why an organism might ferment rather than metabolize it oxidatively in the Krebs?

Citrate, a Krebs cycle (i.e., TCA cycle or citric acid cycle) intermediate, is generated by many bacteria; however, utilization of exogenous citrate requires the presence of citrate transport proteins (permeases). Upon uptake by the cell, citrate is cleaved by citrate lyase to oxaloacetate and acetate. The oxaloacetate is then metabolized to pyruvate and CO2.


The Kreb cycle starts with what?

The Krebs cycle starts with acetyl CoA, and combines with oxaloacetate to form citrate, a six-carbon molecule. Citrate is further oxidized until oxaloacetate is again reached at the end to restart the Krebs cycle.


If an organism is able to convert the sodium citrate?

Citrate, a Krebs cycle (i.e., TCA cycle or citric acid cycle) intermediate, is generated by many bacteria; however, utilization of exogenous citrate requires the presence of citrate transport proteins (permeases). Upon uptake by the cell, citrate is cleaved by citrate lyase to oxaloacetate and acetate. The oxaloacetate is then metabolized to pyruvate and CO2.


How many water molecules produce in Krebs cycle?

Two: 1) oxaloacetate => citrate 2) fumarate => malate


Krebs cycle place in?

The Krebs cycle takes place in the matrix of the mitochondrion.


Why is Krebs cycle also known as citric acid cycle?

the citric acid cycle consists of a series of reactions in mitochondria which catabolizes the oxidation of Acetyl-CoA to CO2 and H2O in aerobic condition. the acetyi-coa combines with a 4-carbon dicarboxyllic acid,oxalloacetate to form 6-carbon tricarboxyllic acid citrate.