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Low sodium and low potassium can lead to an imbalance of electrolytes and kidney failure. Treatment of low sodium and low potassium can be treated with dietary changes and medication.

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Q: What health problems come from low sodium and low potassium?
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The "fast" voltage-gated sodium channels open at -55 mV and close at about +60 mV. I found your question by attempting to find an answer to its second part which is "when [do]...potassium channels open..." and I have yet to find the answer to this myself! There are lots of graphs in physiology books which indicate it is at a voltage very close to that of the sodium channel but I have yet to find an actual figure! The important thing to know is that the potassium channels open at a similar time but are much slower at allowing potassium to flow out of the cell. The effect is that the influx of sodium rapidly brings the resting membrane potential from it's threshold potential of -55 mV to its peak of about +60 mV, at which point they close and become refractory. The slower potassium efflux then "catches up" and brings the membrane potential back down towards its resting value and actually causes a small over-shoot known as hyperpolarisation. The net change in cytosol concentration of the ions is minimal and quickly reversed by the magnificent Sodium-Potassium-ATPase. If you come across the answer to the opening voltage of the potassium channels, please let me know!


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