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Pepsin is an Enzyme that breaks down proteins during digestion. It is produced by the walls of the stomach. It requires a strongly acidic environment such as that present in the stomach. It digests large protein molecules into smaller protein molecules (smaller polypeptides) and is therefore a protease - an enzyme that breaks down a protein. In the stomach, chief cells release pepsinogen. This zymogen is activated by hydrochloric acid (HCl), which is released from parietal cells in the stomach lining. The hormone gastrin and the vagus nerve trigger the release of both pepsinogen and HCl from the stomach lining when food is ingested. Hydrochloric acid creates an acidic environment which allows pepsinogen to unfold and cleave itself in an autocatalytic fashion, thereby generating pepsin (the active form). Pepsin will digest up to 20% of ingested carbon bonds by cleaving preferentially after the N-terminal of aromatic amino acids. Pepsin is stored as pepsinogen so it will only be released when needed, and does not digest the body's own proteins in the stomach's lining.

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15y ago
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11y ago

In the stomach, hydrochloric acid breaks down proteins. In the small intestines, the stomach acid is neutralized so enzymes secreted by the pancreas can break down carbohydrates. Bile is introduced to reduce the droplet size of (emulsify) fats and oils.

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By enzymes in your body fluds

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Q: What in the stomach and small intestine break down food into chemicals the body can use?
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What in the small intestine and stomach break down food into chemicals?

The bile in the stomach,which has a acidic base,by this process it breaks down the food in your stomach


Which organs send chemicals tothe small intestine to help digest food?

the stomach cus acids help break down the food and the mouth to because the saliva has chemicals that help too.


Does the stomach have thicker walls than the small intestine in a frog?

The stomach has a slightly thicker wall than the small intestine as the stomach secretes acids that are used to break down food, while the small intestine's job is just to transport the food through the digestive system


How does the small intestine and the stomach work together?

the stomach churns the food making it into smaller particles. also there are enzymes in the stomach that break up protiens and can only survive in stomach acid. they do this so that the food will not burn the small intestine. Bile is released from the liver into the stomach that help to break up fats. as the food passes through the small intestine its nutrients are absorbed by the villi and are taken into the blood stream.


What is in the stomach and small intestine that breaks down food into chemicals that the body can use?

Those are called enzymes.


Function of stomach small intestine large intestine?

they break down food and absorb the nutrients so our body can use it.


What parts of the body produce enzymes?

The stomach contains enzymes that break down protein.


How is the function of the small intestine different from the function of the large intestine?

The stomach and small intestine both help with digestion. However, the stomach breaks down the food with acids and is mostly a large cavity, while the small intestine absorbs the nutrients and is a long winding path.


What organ digests proteins?

Stomach and small intestine Protein digestion starts in the stomach, then the small intestine completely digests it.


Food passes from the stomach into the small?

The small intestine


If the food passing in stomach does the food go first in large intestine or in small intestine?

The order is as follows: Stomach, small intestine, large intestine.


What organs are connected to the stomach?

your esophagus and small intestine are attached to your stomach.