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What is S9 liver fraction?
Liver S9 fractions are subcellular fractions that contain drug-metabolizing enzymes including the cytochromes P450, flavin monooxygenases, and UDP glucuronyl transferases. Liver S9 fractions are a major tool for studying xenobiotic metabolism.
What has the author Alan Sui Kwong Man written?
Alan Sui Kwong Man has written: 'Investigation of the effect of ibuprofen on drug metabolizing enzymes in rat liver in vivo and in vitro'
How does the drug rifampin interact with the drug dapsone?
Rifampin increases the metabolizing of dapsone in the body, requiring an adjustment of the dapsone dosage.
Why shouldn't you take grapefruit with vardenafil hcl?
I don't know specifically about vardenafil, but grapefruit has substances that interfere with liver enzymes involved in metabolizing many drugs. Combining grapefruit with these drugs can often lead to dangerous elevations of the drug levels.
Is achaol a drug?
I believe you mean alcohol. In which case, yes it is. It is a drug which affects your brain's cognitive functions. You liver tries to break down alcohol using enzymes. Taking too much alcohol damages your brain and liver.
What is the organ that performs most of the metabolism of a drug?
Your stomach and small intestine do most of the metabolizing of substances you take in. The pancreas is responsible for producing the insulin used to break down complex carbohydrates into glucose, which is the only sugar (and substance) your body actually uses.
Side effects of flucillin?
Flucloxacillin can cause diarrhea, nausea, rash, hives, pain and inflammation at the injection site, secondary infection, allergy, and increases in liver enzymes and bilirubin. This drug is an antibiotic in the penicillin class.
Is there a drug called Omacor?
Yes, it is used in the treatment of high cholesterol. Omacor reduces triglycerides by different, independent effects in the liver. The synthesis of triglycerides is inhibited through reduced production of triglycerides in the liver, as EPA and DHA are poor substrates for the enzymes responsible for triglyceride synthesis. EPA and DHA also inhibit esterification of other fatty acids. Omacor increases peroxisomomal beta-oxidation of fatty acids in the liver.
What is the primary site for the drug warfarin?
Liver
What can pharmacogenetics tell us?
genes can determine other aspects of each individual, down to the level of the enzymes produced in the liver. Since these enzymes determine how quickly a drug is removed from the body, they can make major differences in the way people respond to drugs.
Chronic administration of barbiturate or antibotic may cause the liver to do what?
Increase the production of enzymes that break down certain other drugs or foreign substances or it can increase the bodies tolerance to the drug
What is the main organ of drug metabolism?
Liver
