There is no one specific interstate highway which goes from North Carolina to South Dakota.The answer also depend on where you start and where you want to end up.
One route you can take it to take I77 out of North Carolina, then I64, then US35, I70, I65, and then I90 which will take you into South Dakota.
Or you can start out the same as above, but take I74 out of Indianoplis, then I80, then I380, then US218, US18, then I35 to I90, which will take you into South Dakota.
The longest continuous highway in North Carolina is Interstate 40, which runs 421 miles from Tennessee to US117/NC132 in Wilmington (which marks the eastern end of I-40).
North Dakota is to South Dakota as North Carolina is to South Carolina.
Well, honey, North Carolina is to South Carolina as North Dakota is to South Dakota. They're both neighboring states that share a direction in their names. It's not rocket science, just geography.
North Carolina is to South Carolina as is to North Dakotais to South Dakota.
North Dakota South Dakota North Carolina South Carolina
Interstate 29 runs along the eastern edge of North Dakota. It's the only North-South interstate in the state.
North Dakota is to South Dakota
It's about 90 minutes driving time via interstate highway.
The major highways in the state of Iowa are Interstate 35 and Interstate 29. They join the north and south part of the state. Interstate 80 and Interstate 380 join the east and west side of the state.
I-35 is the primary north to south interstate highway in Iowa.
North Dakota is further north than North Carolina.
North Dakota is further north than North Carolina.