myosin?
Calcium ions bind to the thin filament ( actin ), turn it and expose the binding site to the thick filament (myosin ).
Contraction:Calcium ion (from sarcoplasmic reticulum) binds to troponin of actin filament.Re-orientation occurs in actin filament allowing it to bind to the myosin filament.Globular head of myosin filament binds to actin filament.Myosin filament splits an ATP molecule and as result it bends causing actin filament (attached to it) to slide over it. When the overlap of actin and myosin filament is maximum, filaments will occupy less space thus muscle is in contracted state.Relaxation:ATP binds to myosin filament and myosin returns to its original position (relaxed state).Sarcoplasmic reticulum re-accumulates the calsium ion by active transport. As the result actin filament is dettached from myosin filament.When the overlap of myofibrils is minimal, muscle will be in relaxed state.
Actin and myosin
Myosin makes up the THICK filaments, and actin makes up the thin filaments of myofibrils.
The thick filament is composed of the myosin molecule. The thin filament is composed of the actin molecule. Flexing the head of myosin provides the powerstroke.
the ion concentrations (Cl, Na, Ca) in your body stimulate the actin and myosin proteins contract and relax, causing the muscles to move as a consequence.
Myosin is responsible for actin-based muscular mobility/contraction.
is antagonized by the actions of myosin phosphatase
myosin crossbridge binding
Myosin
The two muscle filaments are Myosin and Actin. Myosin is the thicker of the two. When a muscle contracts, a hook like particle extends off the myosin and grabs the actin pulling it in causing the contraction/ tension of the muscle