Che bello! in the singular and Che belli! in the plural are Italian equivalents of the English phrase "How handsome!" Context makes clear which form suits. The respective pronunciations will be "key BEL-lo" in the singular and "key BEL-lee" in the plural in Pisan Italian.
"Very handsome" in English means molto bello in Italian.
"My handsome brother" in English is mio bel fratello in Italian.
"You are so handsome!" in English is Sei così bello! in Italian.
"You are a handsome man!" in English means Sei un bell'uomo! in Italian.
"You are handsome and intelligent!" in English is Sei bello e intelligente! in Italian.
"Good morning, handsome!" in English is Buongiorno, bello! in Italian.
Fico in Italian means "handsome" in English.
"Handsome prince" in English means bel principe or principe bello in Italian.
"Have a good night, handsome!" in English is Buona notte, bello! in Italian.
"You're so handsome!" in English is Sei così bello! in Italian.
"Two handsome men" in English means due bellissimi uominiin Italian.
Bella coppia