0
Want this question answered?
Be notified when an answer is posted
Add your answer:
Earn +20 pts
What does testing the lymphoproliferative response of mononuclear cells to polyclonal stimulators mean?
6
Why does blood agglutinate?
Leukoagglutination is extremely rare in health individuals and is far more common in those suffering from infections, sepsis, lymphoproliferative disorders, alcoholic liver disease, hemophilia, and autoimmune diseases.
What are the consequences of an individual with chediak higashi syndrome have fewer that normal chemotactic receptors and lysosomes that spontaneously rupture?
Patients with Chédiak-Higashi syndrome exhibit hypopigmentation of the skin, eyes, and hair; prolonged bleeding times; easy bruisability; recurrent infections; abnormal natural killer cell function; and peripheral neuropathy. Morbidity results from patients succumbing to frequent bacterial infections or to an accelerated-phase lymphoproliferation into the major organs of the body. Most patients who do not undergo bone marrow transplantation die of a lymphoproliferative syndrome, although some patients with Chédiak-Higashi syndrome have a relatively milder clinical course of the disease. source: www.emedicine.medscape.com
What does testing the lymphoproliferative response of mononuclear cells to polyclonal stimulators mean?
6
What has the author John F Stephens written?
John F. Stephens has written: 'Molecular genetic studies of Epstein-Barr virus-related post-transplant and lymphoproliferative disorders' -- subject(s): Herpesvirus 4, Human, Lymphoproliferative disorders
What does it mean to have too much protein in your blood?
Increased total protein values may be found in multiple myeloma, and conditions with high globulin concentration(lymphoproliferative disorders.)
Is there a cure for XLP?
To date (April 2014) there is no cure for X-linked lymphoproliferative disease (XLP); however, research into a cure is being conducted. In one study, allogeneic hematopoietic stem cell transplantation (HSCT) showed promise of curing the disease. To read the study, visit the Related Link.
What is ebv Panel?
Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that affects more than 95% of the world's population and is the causative agent of infectious mononucleosis (IM). It is also associated with Burkitt's lymphoma, nasopharyngeal carcinoma, and lymphoproliferative disorders occurring in primary and acquired immunodeficiency disorders.EBV panel tests for antibodies.
Why does blood agglutinate?
Leukoagglutination is extremely rare in health individuals and is far more common in those suffering from infections, sepsis, lymphoproliferative disorders, alcoholic liver disease, hemophilia, and autoimmune diseases.
Which disease is caused when white blood cells are produced in excess?
There are several. Leukemia and lymphoma are probably the most common, but there are other lymphoproliferative disorders that can cause an uncontrolled production of white blood cells. Other causes of elevated white blood counts include infection, stress, steroid use, and medications (especially medications that cause you to make more white blood cells - like neupogen or neulasta).
What is a hematology lab test ESR for?
-Erythrocyte Sedimentation Rate (ESR) is the rate at which red blood cells precipitate in a period of one hour.-This is a nonspecific test for inflammatory and lymphoproliferative disorders.-To measure ESR, non coagulated blood is placed in an upright tube, the rate at which red blood cells fall is measured and expressed in millimeters per hour.-Normal value of ESR is 3-7 mm/hr-Pro sedimentation factor is fibrinogen and anti sedimentation factor is -ve charge on RBCs.-ESR is raised in pregnancy, rheumatoid arthritis etc. and decreased in polycythemia, sickle cell anemia, hereditary spherocytosis, CHF.
best oncologist in faridabad?
Dr. Abhishek Bansal MBBS, MD Medicine, DNB Medical Oncology Oncologist in Faridabad Dr. Abhishek Bansal is an expert Medical Oncologist. He is well trained in treating all solid and hematological malignancies with the latest and up-to-date evidence-based therapies which include chemotherapy, immunotherapy, and targeted therapy. He is well experienced in providing palliative and supportive care to cancer patients as well as procedures like bone marrow aspiration and biopsy along with intrathecal chemotherapy. Breast, Ovary, Brain and Spine, Lung, Head & Neck, Gastrointestinal, Genitourinary, Chronic blood leukemias like Chronic Myeloid Leukemia, Chronic Lymphoproliferative Disorder, Myeloproliferative Disorders, Multiple Myeloma, Hodgkin's Lymphoma & Non -Hodgkins Lymphomas. Consultant - Medical Oncology & Haematology Metro Heart Institute with Multispecialty Faridabad
What is autoimmmune disorders?
Autoimmune Disorders List (63)Alopecia AreataAnklosing SpondylitisAntiphospholipid SyndromeAutoimmune Addison's DiseaseAutoimmune Hemolytic AnemiaAutoimmune HepatitisAutoimmune Inner Ear DiseaseAutoimmune Lymphoproliferative Syndrome (ALPS)Autoimmune Thrombocytopenic Purpura (ATP)Behcet's DiseaseBullous PemphigoidCardiomyopathyCeliac Sprue-DermatitisChronic Fatigue Syndrome Immune Deficiency Syndrome (CFIDS)Chronic Inflammatory Demyelinating PolyneuropathyCicatricial PemphigoidCold Agglutinin DiseaseCREST SyndromeCrohn's DiseaseDego's DiseaseDermatomyositisDermatomyositis - JuvenileDiscoid LupusEssential Mixed CryoglobulinemiaFibromyalgia - FibromyositisGrave's DiseaseGuillain-BarreHashimoto's ThyroiditisIdiopathic Pulmonary FibrosisIdiopathic Thrombocytopenia Purpura (ITP)IgA NephropathyInsulin Dependent Diabetes (Type I)Juvenile ArthritisLupusMeniere's DiseaseMixed connective Tissue DiseaseMultiple SclerosisMyasthenia GravisPemphigus VulgarisPernicious AnemiaPolyarteritis NodosaPolychondritisPolyglancular SyndromesPolymyalgia RheumaticaPolymyositis and DermatomyositisPrimary AgammaglobulinemiaPrimary Biliary CirrhosisPsoriasisRaynaud's PhenomenonReiter's SyndromeRheumatic FeverRheumatoid ArthritisSarcoidosisSclerodermaSjogren's SyndromeStiff-Man SyndromeTakayasu ArteritisTemporal Arteritis/Giant Cell ArteritisUlcerative ColitisUveitisVasculitisVitiligoWegener's Granulomatosis
Can the c-myc translocation in Burkitt's lymphoma be hereditary at all?
No. The c-myc translocation is always a somatic event. Such a translocation, if inherited would be either lethal or lead to a congenital aberrancy of the immune system, like a lymphoproliferative autoimmune/immunodeficiency. There has been one report in 1986 of two sisters with Burkitts in a family with lymphocyte abnormalities: Am J Med. 1986 Jul;81(1):158-62.Familial Burkitt's lymphoma. Association with altered lymphocyte subsets in family members. Anderson KC, Jamison DS, Peters WP, Li FP. This paper, however, did not find a hereditary 8;14 translocation. There is no followup to this paper, which suggests that the lymphocyte subset findings were not significant. There is likely other reasons for this always being somatic; the regions of translocation, including a lambda immunoglobulin gene locus are more open in leukocyte lineages. It is likely only favored to promote growth in such lineages. There is, however endemic Burkitts in Africa; this could well have the appearance of hereditary nature.
What are the consequences of an individual with chediak higashi syndrome have fewer that normal chemotactic receptors and lysosomes that spontaneously rupture?
Patients with Chédiak-Higashi syndrome exhibit hypopigmentation of the skin, eyes, and hair; prolonged bleeding times; easy bruisability; recurrent infections; abnormal natural killer cell function; and peripheral neuropathy. Morbidity results from patients succumbing to frequent bacterial infections or to an accelerated-phase lymphoproliferation into the major organs of the body. Most patients who do not undergo bone marrow transplantation die of a lymphoproliferative syndrome, although some patients with Chédiak-Higashi syndrome have a relatively milder clinical course of the disease. source: www.emedicine.medscape.com
