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High blood pressure, blocked arteries, Heart diseases, stroke.

There isn't a "major" disease. A serious problem in the circulatory system is related the person, his overall health status, age, and so on.

For a normal individual, high blood pressure may be the "major" disease. For another person, a blocked or "clogged" artery is the major disease. So, the definition for "major" disease is relative.

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12y ago

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