Vice-principal
Vice Versa
very, vast, vice
vote vase vice veal
A vice.
The word "vice" as a prefix is hyphenated before the word it modifies. For example, "vice-president" or "vice-chancellor."
The opposite word of vice is virtue.
Al Gore
The word you're looking for is "ice" as a prefix in "ice" + "second," which does not exist in English for a term that directly means "second in command." However, if you're thinking of hierarchical titles, "vice" (as in "vice president") conveys a similar meaning but does not start with "ice." Unfortunately, there isn't a fitting term that starts with "ice" and means second in command.
Vice-President Vice-Executive
A word that starts with the root word pent is pentagon.
A word that starts with AN and ends with OR: ancestor.
A compound word that starts with look is look out.