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What antipsychotic drug may be associated with agranulocytosis?
Agranulocytosis has been associated with clozapine. This is a potentially fatal reaction, but can be prevented with careful monitoring of the white blood count.
What is the meaning of lymphocytes granulocytopenia?
Granulocytopenia-- A condition characterized by a deficiency of white blood cells.
What it is agranulocytosis?
Agranulocytosis is a serious condition characterized by a significant decrease in white blood cells called granulocytes. This condition weakens the immune system, making individuals more susceptible to infections. Common symptoms include fever, sore throat, and mouth ulcers. Treatment often involves stopping the offending medication and managing any associated infections.
What has the author Suzanne Leah Iverson written?
Suzanne Leah Iverson has written: 'In vitro and in vivo investigations into idiosyncratic drug reactions: the role of reactive metabolites produced by the target tissue in terbinafine-induced cholestatic hepatitis and antipsychotic-induced agranulocytosis'
What precautions should be taken with atypical antipsychotic drugs?
Although the atypical antipsychotics are generally safe, clozapine has been associated with severe agranulocytosis, a shortage of white blood cells.
What is the contraindications of carbimazole?
Carbimazole is contraindicated in patients with a known hypersensitivity to the drug or its components. It should also be avoided in individuals with severe liver dysfunction, as it can exacerbate liver issues. Additionally, it is not recommended during pregnancy and breastfeeding due to potential risks to the fetus or infant. Regular monitoring of blood counts is essential, as carbimazole can cause agranulocytosis in some patients.
What is Antalgin 550mg?
Antalgin 550mg is a medication commonly used for the relief of pain and inflammation. It typically contains the active ingredient metamizole (also known as dipyrone), which is an analgesic and antipyretic agent. Antalgin is often prescribed for conditions such as headaches, muscle pain, and postoperative discomfort. However, its use may be restricted in some countries due to potential side effects, including the risk of agranulocytosis.
Why is clozapine prescribed?
Clozapine is prescribed primarily for treatment-resistant schizophrenia, particularly in patients who have not responded well to other antipsychotic medications. It is effective in reducing symptoms such as hallucinations and delusions and can also decrease the risk of suicide in individuals with schizophrenia. Due to its potential side effects, including agranulocytosis (a severe drop in white blood cells), patients on clozapine require regular blood monitoring.
Is the painkiller baralgin banned in any countries?
Yes, Baralgin, which contains the active ingredient metamizole (also known as dipyrone), is banned or restricted in several countries due to concerns about its potential to cause severe side effects, including agranulocytosis, a serious decrease in white blood cells. Countries like the United States, Canada, and some European nations have prohibited its use. However, it remains available in several other countries where it is used as an analgesic and antipyretic.
Is dipirona sodica a narcotic?
Dipyrone, also known as metamizole or dipirona sódica, is not classified as a narcotic. It is a non-opioid analgesic and antipyretic medication used to treat pain and fever. Unlike narcotics, which are derived from opium and act on opioid receptors, dipyrone works through different mechanisms, primarily affecting the central nervous system and reducing inflammation. However, its use is restricted or banned in some countries due to potential side effects, such as agranulocytosis.
What does it mean when absolute granulocytes is 0.0?
An absolute granulocyte count of 0.0 indicates a severe deficiency of granulocytes, a type of white blood cell crucial for the immune response. This condition, known as agranulocytosis, can result from various factors, including bone marrow disorders, certain medications, or autoimmune diseases. Patients with this condition are at a significantly increased risk of infections due to their weakened immune system. Immediate medical evaluation is essential to determine the underlying cause and initiate appropriate treatment.
How long is it safe to take lepronex?
Lepronex (clozapine) should be taken under the supervision of a healthcare provider, and the duration of treatment can vary based on individual patient needs and response. Generally, it is used for treatment-resistant schizophrenia and may be prescribed for extended periods, often years, if the benefits outweigh the risks. Regular monitoring for side effects, particularly agranulocytosis, is essential for safe long-term use. Always consult your doctor for personalized guidance regarding treatment duration.
