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What is an explanation of how a muscle contracts?

Updated: 8/18/2019
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12y ago

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The popular model of muscle contraction is "Sliding filament hypothesis" which is proposed by A.F.Huxely and H.E. Huxely.

According to this hypothesis filaments of myofibrils (actin and myosin) slide over each other for the contraction. Muscle cells are not compressed or stretched.

Calcium ions are released from sarcoplasmic reticulum causing re-orientation in actin filament. This enables it to bind to the myosin extensions (known as globular heads or cross bridges).

The myosin filament binds and splits an ATP molecule. As the result the myosin head binds to the actin filament further ahead.

The globular head moves (bends) and the actin filament attached to it also moves and overlaps the myosin filament.

Because of this the actin and myosin filament occupy less space when their overlap is maximum. At this stage the sarcomere (containing unit of myofibrils) is contracted thus the muscle contraction occurs.

As long as the sarcoplasmic reticulum provides the ATP and calsium ions, the myosin can crawl along the actin and muscle contractions continue.

The enzyme ATPase breaks down ATP into ADP to provide energy for muscle contraction. The energy is stored in form of glycogen in muscles which is converted into glucose and then into ATP when muscles contract.

During intensive muscle activity phosphocreatin is broken down into creatin and phosphate group. This phosphate group then combines with ADP to form ATP.

animation will help you in understanding muscle contraction. see the related link below

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