variable segments of light and heavy chains
Heavy chain variable regions & light chain variable region.
single chain variable fragment antibodies are recombinant antibodies, the first application of antibody-based resistance in transgenic plants was reported by Tavladoraki in 1993.
Each antibody has a variable region at the top of the arms of the Y-Shaped structure of the antibody. These variable regions each have a different sequence of amino acids and therefore a different structure. This means that only specific antigens can bind to the binding sites - only those with a complementary shape. The antigen fits into the binding site by induced fit. Once the antigen has bound to the antibody it forms a highly specific antigen-antibody complex. Therefore the role of the variable region is to produce a specific binding site for each type of antigen.
Antibodies lack a transmembrane domain.
The main diagnostic test that distinguishes common variable immunodeficiency from other immunodeficiency diseases is the low antibody level despite the normal number of B cells. Antibody levels are tested in the serum
variable region
Domain is used to refer to the x (or the independent variable).
It is a value in the co-domain [range] of the function.
Antigen binding is a region on an antibody that binds to antigens. Antigen binding is composed of one constant and one variable domain of each of the heavy and the light chain, and these domains shape the antigen binding site at the amino terminal end of the monomer.
x is a letter often used as a variable. It can be in the range or the domain. However, in elementary algebra, the variable x is most often used for the domain and f(x) =y for the range.
Domain is the independent variable in an equation. It is what you put "in" the equation to get the Range.