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What is antigenic variation?

Updated: 10/4/2022
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An antigenic variation is the mechanism by which an infectious organism changes its surface proteins in favour of circumventing a host immune response.

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Beulah Skiles

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Q: What is antigenic variation?
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What is an antigenic variation?

An antigenic variation is the mechanism by which an infectious organism changes its surface proteins in favour of circumventing a host immune response.


What is the difference between antigenic and phase variation?

The Phase Variation is the reversible ability of some bacteria to turn an and off the expression of genes coding for the surface antigens . While the Antigenic Variation is the modification of the gene for an expressed surface antigen by genetic recombination with one of many variable unexpressed DNA sequences. In this manner , the expressed surface antigen can assume many different antigenic structures


Does the influenza virus readily change the expressions of its genetic material?

RNA genome of influenza virus is segmented in to 7 pieces. It has the unique property of undergoing two types of genetic variation ie antigenic drift and antigenic shift. In antigenic drift the antigenic variations are minor where genetic recombination take place between strains of two similar species whereas in antigenic shift the recombination take place between strains of dissimilar species leading to major antigenic variations and hence seasonal epidemics.


What is the importance of phase variation in bacteria?

Causes antigenic diversity in pathogens that contribute to more virulence- adaptive system must account for new targets.


What is the suffix of antigenic?

The suffix of antigenic is -ic.


Is swine flu H1N1 an antigenic shift or drift?

antigenic shift


Antigenic determinants is the site of an antobody?

Words " Antigenic Determinant " itself yells that it is on antigen


Can monoclonal antibodies be specific for multiple antigenic determinants?

No, they are pure antibody preparations specific for a single antigenic determinant.


What are haptens?

antigenic when bound to proteins


What are antigens with only one antigenic site called?

Antigens with only one antigenic site are called Major histocompatibility complex (MHC)


Small molecules that bind with self-proteins to produce antigenic substances are called?

Small molecules that bind with self-proteins to produce antigenic substances are called happens. The unique area that a lymphocyte recognizes and binds to an antigenic determinant.


What the name of a diamond in geometry?

the technical is a antigenic, frogulation.