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A goiter is an enlargement of the thyroid gland which is situated at the front of the throat, below the larynx. It is made up of two lobes on either side of the windpipe, joined in front by an isthmus. The thyroid gland secretes hormones that regulate metabolic processes, such as growth and energy expenditure. This gland is controlled by the pituitary gland, which is located in the brain. The pituitary prompts the thyroid to make its hormones including thyroxine (T4) and tri-iodothyronine (T3) by releasing a thyroid stimulating hormone (TSH). However, if a persons diet is too low in iodine the thyroid can't manufacture hormones. Never the less the pituitary keeps sending chemical messages to the thyroid, without any result . The thyroid gland then enlarges as it unsucsesfuly trys tos to comply with the pituitary's glands instruction. Apart from iodine deficiency, other causes of goiter involve conditions of the thyroid - such as nodules, cancer, hyperthyroidism and hypothyroidism.

The symptoms of a goiter include: * Enlargement of the throat, ranging from a small lump to a huge mass. * Swallowing problems, if the goiter is large enough to press on the esophagus. * Breathing problems, if the goiter is large enough to press on the windpipe (trachea).

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14y ago
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13y ago

It is both hyper thyroid and hypothyroid disease.

Hypothyroid

Thyroid stimulating (TSH) and releasing hormones (TRH) are regulated by thyroid hormone. In hypothyroidism there is no regulation so TSH and TRH increase above normal levels. In normal people this would be an indication of low iodine levels causing the body to hang on to all iodine. Ordinarily the iodine would be used to make thyroid hormone, but in hypothyroidism it collects in the colloid and forms a goitre.

Treatment: Thyroxin (thyroid hormone) will inhibit production of TSH and TRH.

Hyperthyroid

A hyperthyroid goitre is caused by over activation of the thyroid gland. This is usually caused by an autoimmune condition that is stimulating thyroid hormone production in absence of TSH (Grave's Disease). The increased demand on the thyroid gland causes it to grow.

Note: Goitres are filled with connective tissue. Even if you cure the thyroid condition the goitre may remain.

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11y ago

Both are correct, Goiter is american English, goitre is British English.

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Q: Is goitre hypothyroidism or hyperthyroidism
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