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How is erythroblastosis foetalis caused?
When Rh negative mother is carrying Rh positive baby, mothers immune system starts rejecting baby's rhesus factor as a foreign particle, when foetomaternal blood is mixed. So baby's blood gets destroyed and blood cell leads to die. This is the cause of erythroblastosis foetalis also known as Hemolytic disease in new born. Baby may die or end up with jaundice.
Why mother with Rh- sensetize not sensetize to the fist fetus with Rh plus but sensetize to the second one?
When Rh negative mother carries Rh positive fetus, mother's immune system will not react because most of the time , during the first pregnancy ,fetomaternal blood will not mix. This will happen at the time of parturition and when mother's immune system detects Rh + , it starts producing antibodies and for this it takes at least 3 week and this will have memory. So in her second pregnancy if in case fetomaternal blood are encountered, mothers immune system start destroying the blood cells of the fetus. This case is known as ErythroBlastosis Foetalis or Hemolytic Disease in new born (HDN)
Which baby gets erythroblastosis fetalis?
The second baby, normally. Erythroblastosis Foetalis is when a baby with a positive blood group is born to a mother of a negative blood group, and the mother has been 'sensitized' during a previous pregnancy. The mother's body identifies the fetus as a 'foreign' protein and her body's immune system tries to fight the foreign protein, much like an allergic reaction.
Which are some diseases caused by an autosomal dominant allele?
The following list (thanks to Wikipedia) are diseases caused by an autosomal dominant allele. Familial hypercholesterolemia Polycystic kidney disease Neurofibromatosis type I Hereditary sherocytosis Marfan syndrome Huntington's disease Hereditary nonpolyposis colorectal cancer Multiple exostoses
Is blood type A negative compatible with O positive to have babies?
An A1 person is an A person. A people are primarily A1 (about 80%) and A2 (20%). There are quantitative and qualitative differences between A1 and A2, but for almost all intents and purposes, these people are blood type A and would receive A red blood cells. (p.s. the negative just means Rh (D) negative)
If both parents have same blood type can child get sick?
Once the pregnancy is established it is not harmful to the baby. The difficulty might occur very early in pregnancy as a new pregnancy is recognised as a foreign body by the mother and protected from being rejected by the pregnancy hormones. If the baby appears too similar it will be recognised as a foreign body but not protected. There is a very long complicated explanation for this but basically if you get over 12 weeks you should be ok. If you keep miscarrying under 12 weeks ask for regerral to specialist center. I am in UK so I am afraid cannot help you more than this.
How does erythroblastosis fetalis develop?
It happens when the father is of a positive blood group (having Rhesus (Rh) factor) and mother of a negative blood group (devoid of Rh factor), the fetes' blood group will be of the positive type, i.e., having Rh factor as having Rh factor is a dominant trait and can mask the negative blood group. So, this creates problems for the kid as well as mother during pregnancy. Usually, the first pregnancy will not have much complications. But, the second pregnancy onwards, the antibodies present in the mother from the first pregnancy will be present and is harmful for the fetes. It happens when the father is of a positive blood group (having Rhesus (Rh) factor) and mother of a negative blood group (devoid of Rh factor), the fetes' blood group will be of the positive type, i.e., having Rh factor as having Rh factor is a dominant trait and can mask the negative blood group. So, this creates problems for the kid as well as mother during pregnancy. Usually, the first pregnancy will not have much complications. But, the second pregnancy onwards, the antibodies present in the mother from the first pregnancy will be present and is harmful for the fetes.
