The second baby, normally.
Erythroblastosis Foetalis is when a baby with a positive blood group is born to a mother of a negative blood group, and the mother has been 'sensitized' during a previous pregnancy. The mother's body identifies the fetus as a 'foreign' protein and her body's immune system tries to fight the foreign protein, much like an allergic reaction.
Erythroblastosis fetalis can be prevented by treating Rh incompatibility between the mother and fetus. This involves giving the mother Rh immunoglobulin (RhIg) during pregnancy and after delivery to prevent her immune system from producing antibodies against the baby's red blood cells.
The first child born of a female is generally not at risk for erythroblastosis fetalis because the mother's immune system has not been exposed to the fetal blood antigens and therefore has not produced antibodies against it. However, by the second pregnancy there is a slight risk if the blood type of the fetus is not compatible with the mother's blood type.
The most severe form of erythroblastosis fetalis is that resulting from Rh incompatibility. But you can have erythroblastosis fetalis with ABO incompatibility as well. And this can occur with any child, even the first, and even with an Rh-negative child. However, if you're referring to Rh-incompatibility erythroblastosis fetalis, the answer to your question is, "Not usually" (assuming she hasn't had a previous Rh-positive child). In Rh-incompatibility, erythroblastosis fetalis occurs with the woman's second Rh-positive child. The first Rh-positive child's blood gets into the mother's bloodstream (e.g. at childbirth). The mother's blood makes antibodies to Rh. Since the first child is already born, this does not affect the first child. Then, when she has a second Rh-positive child, her antibodies cross the placenta and attack that child's blood cells. On the other hand, if the mother is exposed to the Rh factor of the first child's blood earlier in the pregnancy somehow, then I suppose she could develop enough antibodies to cause a problem for that first child.
http://www.nlm.nih.gov/medlineplus is the website the full URL of the document is http://www.nlm.nih.gov/medlineplus/ency/article/001298.htm This URL leads to a very good article on erythroblastosis fetalis, i couldn't put in the full text, as it is copyrighted, but the website seems very good, this should help you
RHO Gam is used to prevent hemolytic disease of the newborn in cases of Rh incompatibility between the mother and fetus. It works by preventing the mother's immune system from producing antibodies that could harm the baby in future pregnancies.
jnun
What is Erythroblastosis?
erythroblastosis is a very serious condition for approximately 4,000 babies annually. In about 15% of cases, the baby is severely affected and dies before birth.
Well there is an ABO and Rh incompatibility, then baby is at risk of jaundice or erythroblastosis fetalis.
Maija Kirves has written: 'Psychological development of Rh-children' -- subject(s): Developmental psychobiology, Erythroblastosis fetalis, Psychological aspects, Psychological aspects of Erythroblastosis fetalis, Rh factor
IgG is the class of immunoglobulin responsible for the development of erythroblastosis fetalis. It can cross the placenta from a mother who is Rh-negative to a fetus who is Rh-positive, leading to hemolytic disease in the newborn.
Erythroblastosis fetalis can be prevented by treating Rh incompatibility between the mother and fetus. This involves giving the mother Rh immunoglobulin (RhIg) during pregnancy and after delivery to prevent her immune system from producing antibodies against the baby's red blood cells.
by giving an Rh negative mother a gamma globulin solution called RhoGAM whenever there is a possibility that she is developing antibodies to her baby's blood.
Generally the baby will also be Rh positive (depending on the parents' specific genotypes) - and thus be at less risk for erythroblastosis fetalis.
Erythroblastosis fetalis is severe anaemia with excess red blood-forming cells in new born babies. Possibly due to incompatibility between baby's and mother's blood.
Parents who are expecting a baby have their blood typed to diagnose and prevent hemolytic disease of the newborn (HDN), a type of anemia also known as erythroblastosis fetalis.
The main concern is the risk of maternal antibodies attacking the Rh-positive fetal blood cells, leading to hemolytic disease of the newborn (HDN) or erythroblastosis fetalis. This can result in severe anemia, jaundice, and other complications in the newborn. Treatment with Rho(D) immune globulin can prevent this by suppressing the maternal immune response.