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What is it that patches placed on the skin can be used to deliver medications to the bloodstream?
Wiki User
∙ 12y ago
Medications like Duragesic and their generic counterparts deliver the dose transdermally, meaning that the drug is delivered through the skin membrane and thus into the bloodstream.
Duragesic patches work by containing the drug in a suspension gel, contained inside a small pouch on the patch. The bottom of the patch is made of a material that is both adhesive and similar to a porous membrane, which will release the drug into the skin when it's heated by normal body heat. The dosage is regulated over the life of the patch by body heat, which is why overheating the patch (fever, external heat sources,etc.) can significantly increase the delivery rate to the bloodstream. In those cases, even in patients who are opiate tolerant, delirium or respiratory depression can occur. In many cases, for most people who aren't tolerant to high doses (or those who abuse them), it can lead to death.
Wiki User
∙ 14y ago
Wiki User
∙ 9y agoDermal patches generally have a surfactant substance that stimulates blood to the surface of the skin. This causes capillary absorption of the medication leading the bloodstream in general.
Wiki User
∙ 12y agoconditions ranging from heart problems (nitroglycerin) to smoking cessation (nicotine patches).
Wiki User
∙ 13y agobecause of the substance that enters through the bloodstream and through the capillary networks in the skin......................
Wiki User
∙ 12y agoThe drug permeates the capillaries (tiny blood vessels in the skin) thereby
entering the bloodstream.
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Lets say you are vitamin B12 deficient and your taking 1000 mcgs of it a day and your body isn't absorbing the oral dosage so you get monthly vitamin shots what happens if they both aren't absorbed?
If you are getting shots, the B-12 is being placed directly into the bloodstream for you body to use. It may take a few days or weeks to see benefit if you are suffering from pernicious anemia or the like as your body needs to rebuild it's red blood cell supply using the B-12 you are injecting.A safe and effective alternative to shots are transdermal patches. Like the nicotine patch, they deliver the B-12 through your skin. The patch infuses your blood slowly with vitamin B-12 over twenty four hours, and is usually cheaper, less painful and less of a hassle than doctor office visits. Ask your doctor if transdermal patches could work for you.
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