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The process by which cholesterol is transported into the cell by binding of LDL to its receptor and the internalization of the receptor-LDL complex is?
facilitated transport
What is an autosomal dominant disorder that results in a defective or deficient LDL receptor known as?
An autosomal dominant disorder that results in a defective or deficient LDL receptor is known as familial hypercholesterolemia. (FH). Most patient with FH do not live beyond 30 without intervention.
What is the importance of Receptor-mediated Endocytosis in the genetic disorder Familial Hyper-Cholesterolemia?
In mammalian cells, the LDL (low density lipoprotein) receptor transports cholesterol into the cell via receptor-mediated endocytosis. The cholesterol is then used by the cell for various metabolic functions and the receptor is recycled to the plasma membrane.In patients suffering from Familial Hypercholesterolemia, the genes encoding the LDL receptor are mutated, as a result of which cholesterol is unable to bind to the LDL receptor. This leads to accumulation of cholesterol in the circulation, hence causing disease. Patients suffering from this disease are treated using drugs called Statins, which inhibit an important enzyme involved in cholesterol biosynthesis.
Which lipoprotein contains the highest percentage of cholesterol?
HDL has the highest percentage of proteins. LDL has the highest percentage of cholesterol plus cholesteryl esters. LRP is the abbreviation for LDL receptor related protein.
Specialized receptor cells responsible for night vision are called?
The human eye contains specialized receptor cells that are responsible for night vision. These cells are referred to as rods.
What receptor is responsible for the secretion of salivary amylase?
muscarinic receptors
Which type of receptor is responsible for one sense of balance?
the thermoreceptors
What receptor is responsible for adjusting the light and brightness in your eye?
Photoreceptor
Which type of sensory receptor os responsible for responding to pressure?
mechanoreceptor
which of the following are responsible for recognizing a change to the system?
receptor cells - apex
What is the endosomes function?
Endosomes provide an environment for material to be sorted before it reaches the degradative lysosomeAnswers.com. For example, LDLis taken into the cell by binding the LDL_receptorat the cell surface. On reaching early endosomes, the LDL dissociates from the receptor, and the receptor can be recycled to the cell surface. The LDL remains in the endosome and is delivered to lysosomes for processing. LDL dissociates because of the slightly acidified environment of the early endosome, generated by a membrane proton pump V-ATPase. The Mannose_6-phosphate_receptorcarries Ligand_(biochemistry)from the Golgi destined for the lysosome by a similar mechanism.
What is the Function of Endosomes?
Endosomes provide an environment for material to be sorted before it reaches the degradative lysosomeAnswers.com. For example, LDLis taken into the cell by binding the LDL_receptorat the cell surface. On reaching early endosomes, the LDL dissociates from the receptor, and the receptor can be recycled to the cell surface. The LDL remains in the endosome and is delivered to lysosomes for processing. LDL dissociates because of the slightly acidified environment of the early endosome, generated by a membrane proton pump V-ATPase. The Mannose_6-phosphate_receptorcarries Ligand_(biochemistry)from the Golgi destined for the lysosome by a similar mechanism.
