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"The sequence of nitrogenous bases forms the primary structure of the molecule, analagous to the sequence of amino acids in a polypeptide."

-Biological Science: The Cell, Genetics, and Developmentby Scott Freeman

The secondary structure is composed of 2 phosphodiester linked antiparallel nucleotide strands (base pairs) twisted into a double helix. The molecule is stabilized by hydrophobic interactions in its interior and by hydrogen bonding between the complementary bas pairs A-T and G-C.

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13y ago
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13y ago

The primary structure of a DNA molecule is a chain of nucleotides before the complementary base pairing takes place that forms the alpha helix. It is the sequence of nucleotides in this chain that determines the primary structure.

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14y ago

A protein is a chain of smaller molecules called amino acids. Each type of protein has a unique sequence of amino acids in the chain. This sequence is called the primary structure of the protein.

The chain of amino acids can then be folded in two main ways.

In an alpha-helix the chain is twisted into a spiral (helix). The helix is held in shape by weak electrical attractions called hydrogen bonds, which form between non-adjacent amino acids.

In a beta-pleated sheet the amino acid chain is more stretched out and forms a zig-zag pattern, because of the directions of the bonds in the backbone of the chain. Several beta-sheets can be linked together side by side by hydrogen bonding, making a tough but flexible structure.

If the amino acid chain does not form either of these patterns it forms a random coil.

Most proteins have a mixture of all three patterns in the same molecule.

More detail:

Alpha-helix

  • In an alpha-helix the side groups (R groups) of the amino acids stick out from the helix.
  • The N - H groups point upwards and the C =O groups point downwards and hydrogen bonds form between them.
  • There are about 3.6 amino acids for each turn of the helix

Beta sheet

  • The R groups project above and below the plane of the chain
  • The N - H and C = O groups project sideways and form hydrogen bonds with adjacent chains (or later portions of the same chain)
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12y ago

DNA is not a protein, and therefore does not have primary or secondary protein structure.

Primary structure - the sequence of the nucleotides (amino acids in protein)

Secondary structure - the interactions between bases (i.e. which parts of strands are bound to each other)

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10y ago

The primary structure is just a polypeptide chain.

The secondary structure is the hydrogen bonding between the backbone, amino acid base(s), that can form alpha helices and beta pleated sheets.

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13y ago

A primary structure of a protein refers to its amino acid sequence , for example, HAVLQS. Second sturcture means the specific shape these strands coil, which turn into alpha and beta.

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13y ago

double antiparallel helical strands

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Q: What are differences among primary and secondary structure of protein?
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Which levels of structural organization are lost when a protein is denatured?

The secondary and tertiary structures.


Does the secondary structure of a protein involve only the sequence of amino acids found in that protein?

While it is possible to predict likely secondary structures of a protein from its primary structure, only knowing the secondary structure, the general 3-D shape of local areas of the protein, cannot yield the primary structure.


Why protein is called primary structure?

Proteins *have* primary, secondary, tertiary, and quarternary structures. The primary structure is simply the chain of amino acids without any other structure. Secondary structure results from folding of the chain to form rudimentary structures such as alpha helices, beta sheets and turns. Tertiary structure results from the further folding of the protein with secondary structures into different 3D shapes by interactions between different parts of the secondary structure. Quarternary structure results from different proteins with tertiary structures coming together to form a protein complex.


What aspect of protein structure are stabilized or assisted by hydrogen bonds?

secondary, tertiary, and quaternary structures, but not primary structure


How is tertiary protein structure dependent on primary protein structure?

The relationship between the primary and tertiary structure of a protein is the both have a sequence of amino acids in a polypeptide chain.orThe sequence of amino acids in a primary structure determines its three-dimensional shape ( secondary and tertiary structure)

Related questions

Which levels of structural organization are lost when a protein is denatured?

The secondary and tertiary structures.


Differentiate the four types of protein structure?

There are four types of protein structure. These include primary structure, secondary structure, tertiary structure, and quaternary structure. Primary structure is the amino acid sequence. Secondary structure is the shape of the molecule. Tertiary structure is the interaction between groups. Quaternary structure is the interactions between protein subunits.


What are the four levels of protein structure?

primary, secondary, tertiary, and quaternary


What causes the secondary structure of protein to differ in length from the primary?

The primary structure is a one or two dimensional structure, whereas the secondary structure is a three dimensional structure in which different parts of the protein molecule bend and twist due to the formation of hydrogen bonds between atoms. This makes the secondary structure shorter than the primary structure.


The alpha helix and beta pleated sheet represent which level of protein structure?

The alpha helix and beta sheets are found at the Secondary level of protein folding. It's when the protein is taking its shape. Secondary structure


What is the level of protein structure is the amino acid sequence of the protein?

Quaternary tertiary secondary primary is the sequence.


Differences between primary and secondary active transport?

In primary active transport, the transport protein gets phosphorylated; in secondary active transport, the transport protein is not phosphorylated


What are the subgroups of protein?

There are four distinct levels of protein structure. The main two are primary, amino acid, secondary structure, and quaternary structure.


Does the secondary structure of a protein involve only the sequence of amino acids found in that protein?

While it is possible to predict likely secondary structures of a protein from its primary structure, only knowing the secondary structure, the general 3-D shape of local areas of the protein, cannot yield the primary structure.


Why protein is called primary structure?

Proteins *have* primary, secondary, tertiary, and quarternary structures. The primary structure is simply the chain of amino acids without any other structure. Secondary structure results from folding of the chain to form rudimentary structures such as alpha helices, beta sheets and turns. Tertiary structure results from the further folding of the protein with secondary structures into different 3D shapes by interactions between different parts of the secondary structure. Quarternary structure results from different proteins with tertiary structures coming together to form a protein complex.


Primary protein structure is dependent on?

Primary protein structure is the order of amino acids that compose the protein and their arrangement into 2 dimensional structures like sheets or helixes is secondary. Tertiary structure is the mixed composition of secondary forms to make a three dimension protein and quaternary structure is how the protein becomes part of a functional unit like hemoglobin inside of a blood molecule.


What aspect of protein structure are stabilized or assisted by hydrogen bonds?

secondary, tertiary, and quaternary structures, but not primary structure